TABLE 1.

Sample characteristics for genotyped subjects (n = 436) admitted to a secondary health-care institution due to an acute episode of LBP with radiculopathy. Comparison of subjects who responded to the follow-up questionnaire at 12 months with subjects who did not respond.

Characteristics	Total sample (n = 436)	Included subjects (n = 338)	Subjects lost to follow up (n = 98)	p-value
Sex, males, n (%)	251 (58.0)	194 (57.2)	57 (60.6)	0.553 a
Age, years, mean (SD)	42.7 (11.4)	43.8 (11.4)	38.6 (10.7)	<0.001 b
Education, > 12 years, n (%)	322 (74.5)	255 (75.4)	67 (71.3)	0.412 a
BMI, kg/m2, mean (SD)	26.0 (4.3)	26.1 (4.3)	25.9 (4.5)	0.788 b
Smoker, n (%)	76 (17.7)	51 (15.2)	25 (26.6)	0.010 a
Back pain, 0–10 NRS, median (IQR)	6 (2.0–8.0)	5.5 (2.0–8.0)	6.0 (3.0–8.0)	0.052 c
Leg pain, 0–10 NRS, median (IQR)	8 (6.0–9.0)	8.0 (6.0–9.0)	8.0 (6.0–9.0)	0.239 c
ODI, 0–100%, mean (SD)	49.3 (21.6)	49.4 (22.0)	49.1 (20.2)	0.907 b
Pain duration, back/leg pain >3 months, n (%)	208 (49.1)	156 (47.0)	52 (56.5)	0.106 a
Daily medication use, n (%)	276 (63.2)	216 (64.5)	60 (63.8)	0.908 a
Surgical treatment, n (%)	218 (62.1)	160 (62.0)	58 (62.4)	0.952 a
Back pain 12 months, 0–10 NRS, median (IQR)	1 (0.0–3.0)	1.0 (0.0–3.0)	-	-
Leg pain 12 months, 0–10 NRS, median (IQR)	1 (0.0–3.0)	1.0 (0.0–3.0)	-	-
ODI 12 months, 0–10 NRS, median (IQR)	10 (2.0–22.0)	10.0 (2.0–22.0)	-	-
Recovery, back/leg pain <3 NRS 12 months, n (%)	304 (61.1)	304 (61.1)	-	-
SOX5 rs34616559, MAF	0.2	0.2	0.1	0.207 a
CCDC26/GSDMC rs7833174, MAF	0.2	0.2	0.2	0.623 a
DCC rs4384683, MAF	0.5	0.5	0.5	0.837 a

Abberiavations: SD; standard deviation, BMI; body mass index, IQR; interquartile range (25–75%), ODI; oswestry disability index, MAF; minor allele frequency.

^aPearson Chi-Square.

^bIndependent sample Student’s t-test.

^cMann-Whitney U test.