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. 2022 Jan 24;9:834171. doi: 10.3389/fchem.2021.834171

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Copyright © 2022 Zhao, Zhang, Wu and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The schematic illustration of the fabrication of F127-MnO₂-ZIF@DOX/C₃N₄ and F127-MnO₂-ZIF@DOX/C₃N₄ with ¹O₂ generation enhancing the chemo-photodynamic therapy. (B) In vitro evaluation of ¹O₂ generation of FMZ/DC in H₂O₂ solution (10–4 m) under pH = 5. (C) The pH-responsive release of DOX from FMZ/DC determined by UV–vis spectrophotometry. Source: (Xu et al., 2017).