TABLE 1.

The drug release ability of various NMOFs as drug carriers.

NMOFs	Drugs	Drugs loading effective (wt%)	Ways to stimulate drug release	Refs
MIL-53	ATP-TP; Bu; CDV; Doxorubicin (doxo)	0.24 of AZT-TP, 14.3 of Bu	-	Horcajada et al. (2010)
MIL-88A		0.6 of AZT-TP, 8.0 of Bu, 2.6 of AZT-TP, 8.0 of CDV
MIL-89		9.8 of Bu, 14 of CDV
MIL-100		25 of Bu, 21 of AZT-TP, 16 of CDV, 29 of doxo
MIL-100-NH3		42 of AZT-TP, 41.9 of CDV
UIO-MOFs	cisplatin	12	-	He et al. (2014a)
Se/Ru@MIL-101	siRNAs	13.93	-	Chen D et al. (2017)
Fe-MIL-88B-NH2	1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA) 5-amino-3-(pyrrolo [2,3-c]pyridin-1-yl)isoquinoline (defluorinated MK6240, DMK6240) methylene blue (MB)	15 of MB	-	Zhao et al. (2020)
ZIF-8	DOX	15	pH	Zheng et al. (2016)
	3-MA	19.798	pH	Chen W H et al. (2018)
	glucose oxidase (GOx), insulin	15.6 of GOx, 52.3 of insulin	ROS, Glucose, pH	Lu K et al. (2016)
NU-1000	insulin	40	-	Chen W H et al. (2018)
NU-1000x (x = 3, 4, 5, 6, 7)	Lactate dehydrogenase (LDH)	-	-	Li P et al. (2018)
ZIF-90	Rhodamine B (RhB)	-	ATP-responsed	Deng et al. (2017)
	sgRNA), CRISPR/Cas9	-	ATP-responsed	Yang X et al. (2019)
ZJU-64	MTX	13.45	Temperature, pH	Lin et al. (2016)
ZJU-64-CH3	MTX	10.63	Temperature, pH	Lin et al. (2016)
UIO-66-NH2	5-fluorouracil (Fu)	-	Temperature, Zn2+	Tian et al. (2015)
Bio-MOF-1	Procainamide	-	-	An et al. (2009)
MIL-101	BODIPY	5.6–11.6	-	Taylor-Pashow et al. (2009)
Zr-based-MOF	diclofenac sodium (DS)	58.80	Pressure, 37°C	Jiang et al. (2016)