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. 2022 Jan 24;9:834171. doi: 10.3389/fchem.2021.834171

TABLE 2.

The form of cancer treatment of various NMOFs as phototherapeutic agents for cancer therapy.

NMOFs Photosensitizers (PSs) Light source Therapeutic agents Form of cancer treatment Refs
PB@MIL-100(Fe) Prussian blue (PB) NIR PTT Wang B et al. (2016)
PB@mSiO2−PEG Prussian blue (PB) NIR DOX PTT Su et al. (2016)
UiO-66@PAN Polymer polyaniline (PAN) NIR - PTT Wang D et al. (2016)
PPy@MIL-100 Polypyrrole (PPy) NIR - PTT and chemotherapy Chen D et al. (2017)
MOF@HA@ICG Indocyanine green (ICG) NIR - PTT Cai et al. (2017)
Hf6(μ 3-O)4 (μ 3-OH)4 (DBP)6 Porphyrin DBP Visible light 1O2 PDT Lu et al. (2014)
Hf6(μ 3-O)4 (μ 3-OH)4 (DBP)6 Porphyrin DBC Visible light 1O2 PDT Lu et al. (2015)
Hf-TCPP Hf4+, Porphyrin X-ray 1O2 PDT and RT Liu et al. (2016)
PCN-224 Zr4+, Porphyrin UV 1O2 PDT Park et al. (2016a)
Zn-TCPP-BPDTE Porphyrin TCPP UV 1O2 PDT Park et al. (2015)
UiO-66 TCPP UV 1O2 PDT Park et al. (2016b)
UiO-PDT BODIPYs Confocal laser 1O2 PDT Wang et al. (2016a)
Hf-/Zr-based MOFs [M6]-clusters (M = Hf or Zr) X-ray, visible light photons PDT Wang et al. (2014)
Hf-BPY-Ir/Ru Hf atoms X-ray 1O2 PDT Lan et al. (2017)
IDOi@TBC-Hf Hf atoms LED 1O2 and IDOi PDT and immunotherapy Lu Y et al. (2016)
DBP-Hf Hf atoms LED 1O2 and IDOi PDT and immunotherapy Lu et al. (2018a)
g-C3N4@ZIF-8 g-C3N4 - 1O2 and IDOi PDT and immunotherapy Chen et al. (2015)
PCN-222 Porphyrin - 1O2 and DOX PDT and immunotherapy Liu et al. (2017)
MIL-88B Porphyrin - MB and DOX PDT and chemotherapy Sharma et al. (2017)
F127-MnO2-ZIF@DOX/C3N4 g-C3N4 NIR 1O2 and DOX PDT and immunotherapy Zhang Q et al. (2018)