FIGURE 1.

Success rate of sputum induction in asthma and predictors of succesful induction at follow-up. TSLP: thymic stromal lymphopoietin; OCS: oral corticosteroid; ICS: inhaled corticosteroid; AHR: airway hyperreactivity; FEV₁: forced expiratory volume in 1 s; LABA: long-acting β₂-agonist; LAMA: long-acting muscarinic antagonist. ^#: proportion of patients with successful sputum at baseline and follow-up; ^¶: normalisation of mannitol challenge test; ⁺: 200 mL and 12% improvement; ^§: 1600 μg budesonide equivalent.