Table 1.

Diagnostic Yield Comparison Among Genotypes of the 744 Inherited Macular Dystrophy Families Recruited Until 2017, After the Restudy of Unsolved Cases

	Genotype Groups
Period of Genetic Study	Solved ABCA4	Solved Other Genes	Monoallelic ABCA4	Unsolved
STGD diagnosis group (N = 454)
Initial technologies	272 (59.9%)	1 (0.2%)	50 (11%)	131 (28.9%)
Restudy	338 (74.4%)	16 (3.5%)	15 (3.3%)	85 (18.7%)
P value	<0.001	<0.001	<0.001	<0.001
CCRD diagnosis group (N = 183)
Initial technologies	58 (31.7%)	31 (16.9%)	7 (3.8%)	87 (47.5%)
Restudy	73 (39.9%)	43 (23.5%)	3 (1.6%)	64 (35%)
P value	<0.001	0.002	NS	<0.001
OtherMD diagnosis group (N = 107)
Initial technologies	6 (5.6%)	12 (11.2%)	3 (2.8%)	86 (80.4%)
Restudy	10 (9.3%)	36 (33.6%)	3 (2.8%)	58 (54.2%)
P value	NS	<0.001	NS	<0.001

NS, nonsignificant.