FIGURE 1.
Super‐enhancer, miRNA regulation, and cancer biology. A, Definition of super‐enhancers. B, Impacts of super‐enhancers on miRNA expression and function. Super‐enhancers drive a small subset of cell type‐specific miRNAs that are highly abundant in the relevant cell types and mediate potent target gene repression. C, Cancer hallmark traits and SE‐miRNAs with SE loss or gain in cancer cells. B and C are modified from our previous report 6