FIGURE 1.

Immunohistochemical expression of Schlafen 11 (SLFN11) in bladder cancer (BC) and validation of the association between SLFN11 expression and clinical course. A, Representative immunohistochemical images of SLFN11 in BC. Scale bars, 200 µm (left) and 50 µm (right). B, Distribution of the immunohistochemical expression of SLFN11 in 120 BC cases, with 5% used as the cut‐off value. C, Correlation of the expression of SLFN11 protein with overall survival (OS) of 120 patients with BC. D, Correlation of the expression of SLFN11 protein with OS of 50 patients with unresectable locally advanced or metastatic BC treated with platinum‐based chemotherapy. E, Correlation of the expression of SLFN11 protein with OS of 70 patients with local BC treated by surgical resection without chemotherapy