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. 2021 Dec 13;113(2):802–807. doi: 10.1111/cas.15234

FIGURE 3.

FIGURE 3

Cyclin‐dependent kinase 4/6 inhibitors suppress tumor growth in extramammary Paget’s disease patient‐derived xenograft. Tumor‐bearing NOD/Scid mice were randomized into no therapy (control, black line), abemaciclib (green line), and palbociclib (orange line). Tumor volumes were calculated according to the formula: (long axis × short axis2)/2. The results are presented as means, with error bars representing the SD from the mean. *P < .05, **P < .01 vs control