TABLE 2.
Mutation frequencies of recurrently mutated genes in all cases, OR group, and nOR group
| Genes | Mutation presence | All (n = 42) | OR (N = 8) | nOR (N = 34) | P‐value |
|---|---|---|---|---|---|
| APC n (%) | Absence | 37 (88.1) | 7 (87.5) | 30 (88.2) | 1 |
| Presence | 5 (11.9) | 1 (12.5) | 4 (11.8) | ||
| ARID1A n (%) | Absence | 40 (95.2) | 8 (100.0) | 32 (94.1) | 1 |
| Presence | 2 (4.80) | 0 (0.00) | 2 (5.90) | ||
| BCL2 n (%) | Absence | 30 (71.4) | 7 (87.5) | 23 (67.6) | .402 |
| Presence | 12 (28.6) | 1 (12.5) | 11 (32.4) | ||
| CARD11 n (%) | Absence | 35 (83.3) | 8 (100.0) | 27 (79.4) | .312 |
| Presence | 7 (16.7) | 0 (0.00) | 7 (20.6) | ||
| CREBBP n (%) | Absence | 17 (40.5) | 5 (62.5) | 12 (35.3) | .235 |
| Presence | 25 (59.5) | 3 (37.5) | 22 (64.7) | ||
| EP300 n (%) | Absence | 36 (85.7) | 8 (100.0) | 28 (82.4) | .576 |
| Presence | 6 (14.3) | 0 (0.00) | 6 (17.6) | ||
| EP400 n (%) | Absence | 38 (90.5) | 8 (100.0) | 30 (88.2) | .572 |
| Presence | 4 (9.50) | 0 (0.00) | 4 (11.8) | ||
| ERBB2 n (%) | Absence | 38 (90.5) | 7 (87.5) | 31 (91.2) | 1 |
| Presence | 4 (9.50) | 1 (12.5) | 3 (8.80) | ||
| EZH2 n (%) | Absence | 33 (78.6) | 8 (100.0) | 25 (73.5) | .168 |
| Presence | 9 (21.4) | 0 (0.00) | 9 (26.5) | ||
| FOXO1 n (%) | Absence | 40 (95.2) | 8 (100.0) | 32 (94.1) | 1 |
| Presence | 2 (4.80) | 0 (0.00) | 2 (5.9) | ||
| KMT2D n (%) | Absence | 26 (61.9) | 7 (87.5) | 19 (55.9) | .127 |
| Presence | 16 (38.1) | 1 (12.5) | 15 (44.1) | ||
| MEF2B n (%) | Absence | 29 (69.0) | 5 (62.5) | 24 (70.6) | .686 |
| Presence | 13 (31.0) | 3 (37.5) | 10 (29.4) | ||
| SYNE1 n (%) | Absence | 38 (90.5) | 7 (87.5) | 31 (91.2) | 1 |
| Presence | 4 (9.50) | 1 (12.5) | 3 (8.80) | ||
| TNFRSF14 n (%) | Absence | 36 (85.7) | 7 (87.5) | 29 (85.3) | 1 |
| Presence | 6 (14.3) | 1 (12.5) | 5 (14.7) | ||
| m7FLIPI n (%) | Low | 32 (76.2) | 8 (100.0) | 24 (70.6) | .165 |
| High | 10 (23.8) | 0 (0.00) | 10 (29.4) |