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. 2022 Jan 19;25(2):103786. doi: 10.1016/j.isci.2022.103786

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

DMR developmental time course

The scaled mean RPKM read depth is shown for the top 100 statistically significant DMRs for each developmental stage comparison.

(A) PGC greater than E16 (∗ = p < 1e-05) n = 72.

(B) E16 greater than PGC (∗ = p < 1e-05) n = 28.

(C) E16 greater than P10 (∗ = p < 1e-05) n = 15.

(D) P10 greater than E16 (∗ = p < 1e-05) n = 85.

(E) P10 greater than pachy (∗ = p < 1e-05) n = 81.

(F) Pachy greater than P10 (∗ = p < 1e-05) n = 19.

(G) Pachy greater than RS (∗ = p < 1e-05) n = 41.

(H) RS greater than pachy (∗ = p < 1e-05) n = 59.

(I) RS greater than caput (∗ = p < 1e-05) n = 64.

(J) Caput greater than RS (∗ = p < 1e-05) n = 36.

(K) Caput greater than cauda (∗ = p < 1e-05) n = 35.

(L) Cauda greater than caput (∗ = p < 1e-05) n = 65.