Table 1.

Characteristics of HFpEF and HFrEF, stratified by presence of AF

	HFpEF			HFrEF
Variable	AF (n=794,013)	No AF (n=1,094,287)	p	AF (n=858,435)	No AF (n=1,413,994)	p
Age (Mean ± SD, years)	79.6 ± 10.3	73.1 ± 13.8	<0.001	75.8 ± 12.0	69.2 ± 15.1	<0.001
Women	64.3	64.0	<0.001	40.7	42.7	<0.001
Race (%)
White	84.0	68.8		80.0	65.1
Black	7.8	19.5	<0.001	11.2	22.6	<0.001
Other	8.2	11.7		8.8	12.2
Primary Payer (%)
Medicare	87.8	77.2		81.7	68.8
Medicaid	2.5	7.1	<0.001	4.3	9.7	<0.001
Private including HMO	7.9	11.6		10.7	14.6
Self pay	0.8	2.4		1.9	4.5
Hospital Region (%)
Northeast	25.3	23.2		23.4	22.1
Midwest	26.6	24.4	<0.001	25.7	23.2	<0.001
South	32.9	38.0		36.4	40.9
West	15.2	14.4		14.5	13.7
Hospital Setting (%)
Academic	44.8	45.3	<0.001	46.1	47.4	<0.001
Urban	89.2	88.0	<0.001	88.4	88.1	<0.001
Hospital Size (%)
Small	12.9	12.4		11.7	11.0
Medium	26.1	25.6	<0.001	23.7	23.5	<0.001
Large	61.0	62.0		64.6	65.5
Comorbidity
Anemia	32.4	35.8	<0.001	26.8	26.8	0.82
Coronary artery disease	42.1	41.1	<0.001	59.9	58.6	<0.001
Chronic pulmonary disease	38.2	37.6	<0.001	33.0	31.8	<0.001
Chronic renal failure	34.9	39.1	<0.001	37.2	35.7	<0.001
Diabetes	36.8	46.6	<0.001	37.4	42.8	<0.001
Hypertension	68.9	67.9	<0.001	65.1	64.3	<0.001
Hypothyroidism	21.0	16.3	<0.001	17.2	12.3	<0.001
Liver disease	2.0	2.7	<0.001	2.3	2.6	<0.001
Obesity	16	21.4	<0.001	12	13.2	<0.001
Peripheral vascular disorders	12	12.1	0.06	12.6	12.6	0.31
Pulmonary circulation disorders	7.1	6.2	<0.001	3.8	3.0	<0.001
Valvular Disease	9.4	6.7	<0.001	7.1	4.9	<0.001
Elixhauser Comorbidity Summary Score (Mean ± SD)	7.8 ± 7.1	8.2 ± 7.2	<0.001	7.2 ± 6.9	6.9 ± 7.0	<0.001
CHADS2 Score (Mean ± SD)	2.9 ± 0.9	2.7 ± 0.9	<0.001	2.7 ± 0.9	2.5 ± 0.9	<0.001
CHA2DS2-VASc Score (Mean ± SD)	4.5 ± 1.2	4.2 ± 1.3	<0.001	4.1 ± 1.3	3.7 ± 1.4	<0.001
In-hospital Mortality (%)	4.7	4.0	<0.001	5.3	5.1	<0.001

Abbreviations: HFpEF=heart failure with preserved ejection fraction; HFrEF=heart failure with reduced ejection fraction; AF=atrial fibrillation.