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. 2022 Jan 17;33(1-2):61–75. doi: 10.1089/hum.2021.069

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Copyright 2022, by Mary Ann Liebert, Inc., publishers

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Figure 5. — Automated image analysis of spinal cord transduction. (a) Transduction efficiency in percentages of GFP immunopositive motor neurons and interneurons for AAV-F (left) and AAV9 (right) across cervical, thoracic, and lumbar regions. Comparison of transduction efficiency in % positive cells between AAV9 and AAV-F (b) across the entire spinal cord, (c) in spinal cord regions for interneurons, and (d) spinal cord levels for motor neurons. Comparison of transduction levels/cell (mean stain intensity) between AAV9 and AAV-F (e) across entire spinal cord and (f) regions of spinal cord. Mean ± standard deviation are shown. Individual cells are shown as black data points. C, cervical; T, thoracic; LS, lumbar-sacral.