Table 2.
Relationship Between CVAI and New-Onset MI in Different Models
| Variable | Crude Model | Adjusted Model 1 | Adjusted Model 2 | Adjusted Model 3 | ||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| CVAI (Per 1 SD increase) | 1.65 (1.43, 1.90) | <0.01 | 1.58 (1.35, 1.84) | <0.01 | 1.56 (1.33, 1.83) | <0.01 | 1.54 (1.28, 1.85) | <0.01 |
| Quartiles of CVAI | ||||||||
| Q1 | Ref. | Ref. | Ref. | Ref. | ||||
| Q2 | 1.30 (0.67, 2.50) | 0.44 | 1.13 (0.58, 2.19) | 0.72 | 1.15 (0.59, 2.25) | 0.67 | 1.20 (0.61, 2.38) | 0.59 |
| Q3 | 2.87 (1.64, 5.03) | <0.01 | 2.49 (1.40, 4.43) | <0.01 | 2.30 (1.29, 4.11) | <0.01 | 2.45 (1.32, 4.55) | <0.01 |
| Q4 | 4.80 (2.80, 8.24) | <0.01 | 3.99 (2.25, 7.06) | <0.01 | 3.76 (2.12, 6.64) | <0.01 | 3.64 (1.94, 6.83) | <0.01 |
| P for trend | <0.01 | <0.01 | <0.01 | <0.01 | ||||
Notes: Crude model: Unadjusted. Adjusted model 1: adjusted for age, gender, NC, BMI, DBP, SBP, history of diabetes, drinking status, and smoking status. Adjusted model 2: adjusted for all the variables in model 1, plus TG, TC, LDL-C, HDL-C, Lp (a), FPG, HsCRP, and Hcy. Adjusted model 3: adjusted for all the variables in model 2, plus antihypertensive drugs, lipid-lowering drugs, antiplatelet drugs, antidiabetic drugs, regular CPAP treatment, AHI, mean SaO2, and lowest SaO2.
Abbreviations: CI, confidence interval; HR, hazard ratio; other abbreviations as in Table 1.