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. 2022 Jan 24;9:758777. doi: 10.3389/fcell.2021.758777

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Copyright © 2022 Ouyang, Jiang, Bu, Tang, Huang, Chen, Tan, Ou, Mao, Mai, Yao, Yu and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the risk score formula for immunotherapy. (A) Kaplan-Meier survival curve of GSE135222 cohort for PFS. (B) Time-related ROC analysis proved the prognostic performance of the risk score in the GSE135222. (C) The difference of risk score in the subgroup of PD-1 treatment response in GSE126044. (D) Kaplan-Meier survival curve of IMvigor210 cohort for OS. (E) The difference of Risk score in the subgroup of PD-L1 treatment response. (F) The expression of immue-related checkpoints among high and low risk groups in IMvigor210 cohort. *p < 0.1; *p < 0.05; **p < 0.01; ***p < 0.001.