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. 2022 Feb 3;8(1):e002012. doi: 10.1136/rmdopen-2021-002012

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Radiographic outcomes at 6 months, 1 year and 2 years (AO). *Per study design, all patients in the placebo group who were not previously rescued were switched to upadacitinib at week 26. Data are reported AO. (A) Determination of no radiographic progression was assessed by a change from baseline in mTSS ≤0. (B) Least-squares mean change from baseline in mTSS. ADA, adalimumab; AO, as observed; bL, baseline; EOW, every other week; LS, least squares; MTX, methotrexate; PBO, placebo; QD, once daily; mTSS, modified Total Sharp Score; UPA, upadacitinib.