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. 2022 Feb 4;12(2):e054583. doi: 10.1136/bmjopen-2021-054583

Table 2.

Standardised elements of CRRT programmes

Programme element Operational definition Benchmark
CRRT leadership Presence of both CRRT physician and clinical nurse educator 100%
CRRT education Number of CRRT providers with training/ total number of CRRT providers 100%
Filter life Number of filters lasting 72 hours/total number of filters used >50% of filters
Delivered dose Actual delivered dose in mL/kg/hour/prescribed dose in mL/kg/hour >85% of dose and between 25 mL/kg/hour and 30 mL/kg/hour
Downtime Time CRRT not running per day/each day of CRRT prescription <15%
Ultrafiltration Actual ultrafiltration achieve in mL/kg/hour/prescribed ultrafiltration in mL/kg/hour >85% of prescription
Access alarms Number of alarms recorded per machine per day of therapy <5 alarms
Adverse events Number of adverse events as per RLS per quarter 0 events
ICU mortality Patient survival to ICU discharge >50%
Renal recovery Number of patients still requiring RRT at 90 days <10%

CRRT programme elements are shaded from white to light grey to dark grey as per the Donabedian framework of structure, process and outcome. Specific CRRT KPIs are in bold. Benchmarks have been taken from our internal and external validation of the KPIs. Our primary outcome will measure the performance of specific CRRT process KPIs.

CRRT, continuous renal replacement therapy; KPIs, key performance indicators.