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. 2022 Feb 7;23:121. doi: 10.1186/s13063-021-05874-6

Table 3.

Trial operating characteristics assuming constant accrual of 16 per week, where q=0.95,c_=0.05, and c¯=0.95

θa θw Decide superior Stop early superior No stop superior Stop futile Stop expect success Superior following futile Superior following expect success Expected sample size
0.10 0.05 0.99 0.97 0.02 0.01 0.97 0.61 1.00 1673
0.06 0.97 0.84 0.12 0.03 0.84 0.34 0.99 1959
0.07 0.85 0.57 0.27 0.08 0.59 0.14 0.95 2251
0.08 0.55 0.28 0.28 0.21 0.31 0.05 0.86 2412
0.09 0.22 0.09 0.12 0.44 0.13 0.01 0.68 2353
0.10 0.05 0.02 0.03 0.69 0.04 0.00 0.47 2129