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. Author manuscript; available in PMC: 2022 Feb 7.
Published in final edited form as: J Anxiety Disord. 2021 Oct 26;84:102490. doi: 10.1016/j.janxdis.2021.102490

Table 1.

Participant-level characteristics by study.

Study ITT N Treatment Comparator Age % Female % Racial/Ethnic Minority % Met PTSD Diagnostic Criteria % Met SUD Diagnostic Criteria % with Current Drug Use
Back et al. (2019) 81 ITF Manual SUD 40.4 9.9 39.5 100 100 37.1
Boden et al. (2011) 98 NTF TAU 54 0 81 NA 100 80.6
Brief PC 386 NTF No/minimal tx 32.15 13.40 22.25 NA NA NA
Capone et al. (2014) 44 NTF TAU 34.29 4.55 15.85 100 100 38.6
Coffey et al. (2016) 126 TF TAU1 34 46 20.6 100 100 NA
van Dam, Ehring, Vedel, and Emmelkamp (2013) 34 TF Manual SUD 42.3 32.4 26.5 61.8 100 55.9
Foa et al. (2013) 165 TF (+Nal) Manual SUD 42.7 34.5 69.7 100 100 NA
TF (+PL) Manual SUD
Haller PC 101 ITF TAU2 46.4 10.9 37.6 100 100 58.5
Hamblen (2020) 129 TF TAU 44.2 5.4 32.8 100 100 92
Hien, Cohen, Miele, Litt, and Capstick (2004) 75 NTF Manual SUD 36 100 36 88 100 65.3
Hien et al. (2009) 353 NTF TAU1 39.2 100 54.4 80.4 100 91.2
Kehle-Forbes et al. (2018)3 183 ITF TF 44.1 7.75 58.95 100 100 18
McGovern, Lambert-Harris, Alterman, Xie, and Meier (2011) 53 NTF Manual SUD 37.3 56.6 8.7 100 100 47.2
McGovern et al. (2015) 221 NTF Manual SUD 35.3 59.3 4.5 100 100 51.1
Mills et al. (2012) 103 ITF No/minimal tx 33 62.1 5.8 100 100 79.6
Myers, Browne, and Norman (2015) 40 NTF Manual SUD 42.2 100 48.4 80.6 100 NA
Najavits et al. (2018) 3 52 ITF NTF 48.7 26.9 40 100 100 50
Norman et al. (2019) 3 119 ITF NTF 41.6 10.1 34.5 95.8 100 NA
Perez-Dandieu and Tapia (2014) 12 TF TAU 29.5 100 NA 100 100 83.3
Possemato et al. (2019) 3 30 NTF NTF 38.6 6.7 20 76.7 100 NA
Ruglass et al. (2017) 110 ITF Manual SUD 44.4 36.4 81.8 64.5 98.2 66.4
Sannibale et al. (2013) 62 ITF Manual SUD 41.2 53 NA 100 95 15
Schacht et al. (2017) 3 58 TF TF 37.4 79 29 100 100 100
Schafer et al. (2019) 343 NTF Manual SUD 40.97 100 9.6 NA 100 NA
Simpson et al. (2021) 4 101 TF Manual SUD 42.1 56 47 100 100 38.6
Stappenbeck et al. (2015) 78 NTF No/minimal tx 44.3 48.7 57.7 100 100 NA
Vujanovic, Smith, Tipton, and Schmitz (2018) 4 41 ITF Manual SUD 44.9 53.7 75.6 NA 100 NA
Zlotnick, Johnson, and Najavits (2009) 49 NTF TAU 34.6 100 53.1 83.5 100 NA

Note: ITT N = intention-to-treat sample size; NA = not available; PC = Personal Communication; Manual SUD = manualized SUD treatment; No tx = no/minimal treatment; TAU = SUD TAU; NA = information not collected/reported; NTF = not trauma-focused; TF = trauma-focused; ITF = integrated trauma-focused; NAL = Naloxone; PL = placebo drug.

1

Participants received SUD TAU and a general healthy lifestyle or health-oriented attention placebo control.

2

Participants received an integrated CBT intervention to address depression and SUD.

3

Studies that did not contribute to between-group analyses.

4

Unpublished studies at time analyses undertaken.