Table 4.
Top probe sets positively correlated with dd-cfDNA(%) in the Trifecta Study (n=300) ordered by correlation coefficient
| Affy ID | Gene Symbol | Gene Name | Transcript Set Annotation | SCCa |
|---|---|---|---|---|
| 11751857_a_at | GNLYb | granulysin | ABMR-RAT, Rej-RAT | 0.56 |
| 11763715_a_at | GNLYb | granulysin | ABMR-RAT,Rej-RAT | 0.55 |
| 11746954_s_at | CCL4b | chemokine (C-C motif) ligand 4 | ABMR-RAT,Rej-RAT | 0.52 |
| 11761790_x_at | TRDCb | T cell receptor delta constant | ABMR-RAT,Rej-RAT | 0.51 |
| 11718982_s_at | CCL4b | chemokine (C-C motif) ligand 4 | ABMR-RAT,Rej-RAT | 0.51 |
| 11718983_x_at | CCL4b | chemokine (C-C motif) ligand 4 | ABMR-RAT,Rej-RAT | 0.51 |
| 11743168_at | IDO1c | indoleamine 2,3-dioxygenase 1 | ABMR-RAT,GRIT3,Rej-RAT | 0.51 |
| 11749245_a_at | CXCL11c | chemokine (C-X-C motif) ligand 11 | ABMR-RAT,GRIT3,Rej-RAT | 0.50 |
| 11753484_x_at | KLRD1b | killer cell lectin-like receptor subfamily D, member 1 | ABMR-RAT,Rej-RAT | 0.50 |
| 11727116_a_at | PLA1Ac | phospholipase A1 member A | ABMR-RAT, Rej-RAT | 0.50 |
| 11729649_at | PRF1b | perforin 1 (pore forming protein) | ABMR-RAT,QCAT,Rej-RAT | 0.50 |
| 11740452_x_at | KLRD1b | killer cell lectin-like receptor subfamily D, member 1 | ABMR-RAT,Rej-RAT | 0.50 |
| 11724900_a_at | GZMBb | granzyme B | ABMR-RAT,QCAT,Rej-RAT | 0.49 |
| 11726287_a_at | WARSc | tryptophanyl-tRNA synthetase | ABMR-RAT,GRIT3,Rej-RAT | 0.49 |
| 11733353_at | CRTAMb | cytotoxic and regulatory T-cell molecule | ABMR-RAT,RAT,Rej-RAT | 0.49 |
| 11756632_a_at | GNLYb | granulysin | ABMR-RAT,QCAT,Rej-RAT | 0.49 |
| 11744660_s_at | CCL4L1b | chemokine (C-C motif) ligand 4-like 1 | ABMR-RAT, Rej-RAT | 0.49 |
| 11732466_a_at | CXCL11c | chemokine (C-X-C motif) ligand 11 | ABMR-RAT,GRIT3,Rej-RAT | 0.49 |
| 11752664_a_at | S1PR5b | sphingosine-1-phosphate receptor 5 | ABMR-RAT,RAT | 0.49 |
| 11763756_x_at | GNLYb | granulysin | ABMR-RAT,QCAT,RAT | 0.49 |
Transcript sets are described on the home page at https://www.ualberta.ca/medicine/institutes-centres-groups/atagc/research/gene-lists.html. ABMR-RAT, antibody-mediated rejection-associated transcripts; GRIT, gamma-interferon-inducible transcripts, QCAT, Cytotoxic T cell-associated transcripts; Rej-RAT, rejection-associated transcripts.
a
All P values were <0.0001.
b
NK cell expressed.
c
IFNG-inducible.