Table 5.
Variable | SCC | P Value | ||
---|---|---|---|---|
ABMR related | ABMR probability classifier | ABMRProba | 0.52a | <0.0001a |
cg>0-probability classifier | cg>0Prob | 0.35 | <0.0001 | |
g>0-probability classifier | g>0Proba | 0.50a | <0.0001a | |
ptc>0 probability classifier | ptc>0Proba | 0.54a | <0.0001a | |
DSA-probability classifier | DSAProb | 0.39 | <0.0001 | |
ABMR transcripts | ABMR-RATa | 0.51a | <0.0001a | |
All rejection | Rejection-probability classifier | RejProba | 0.52a | <0.0001a |
IFNG-inducible transcripts | GRIT3 | 0.44 | <0.0001 | |
TCMR related | Effector T cell transcripts | QCAT | 0.43 | <0.0001 |
TCMR-probability classifier | TCMRProb | 0.22 | <0.0001 | |
i>1-probability classifier | i>1Prob | 0.34 | <0.0001 | |
t>1-probability classifier | t>1Prob | 0.26 | <0.0001 | |
Macrophage related | Macrophage transcripts | QCMAT | 0.37 | <0.0001 |
Alternative macrophage activation transcripts | AMAT1 | 0.39 | <0.0001 | |
Recent injury | Recent injury-induced | IRRAT30 | 0.18 | 0.002 |
Injury-induced day 3 | IRITD3 | 0.18 | 0.001 | |
Parenchymal | Normal kidney transcripts | KT1 | −0.19 | 0.0001 |
Atrophy fibrosis | ci>1-probability classifier | ci>1Prob | 0.16 | 0.005 |
ct>1-probability classifier | ct>1Prob | 0.13 | 0.02 |
Transcript sets are described on the home page at https://www.ualberta.ca/medicine/institutes-centres-groups/atagc/research/gene-lists.html.
Classifiers and gene sets with correlation >0.50.