Table 10.
Recovery of peripheral B cell counts during the treatment period
| Visit | Day | MMF Group | Placebo Group | Wilcoxon Test (P Value) | ||||
|---|---|---|---|---|---|---|---|---|
| No. of Patients | Mean (SD) | Median (min-max) | No. of Patients | Mean (SD) | Median (min-max) | |||
| 0 | Screening period | 39 | 588.7 (573.9) | 418 (22–3329) | 39 | 534.8 (400.1) | 421 (83–2040) | 0.91 |
| 1 | 1 | 38 | 674 (454.9) | 670.3 (7.2–1722.2) | 36 | 609.9 (551.7) | 534.2 (13.6–2384.2) | 0.24 |
| 2 | 8 | 38 | 5.6 (7.6) | 3 (0–35.3) | 37 | 5.9 (10.2) | 2.4 (0–50.4) | 0.54 |
| 4 | 22 | 39 | 4.7 (8) | 1.8 (0–34.2) | 35 | 4 (8.5) | 1.6 (0–43.7) | 0.55 |
| 5 | 29 | 25 | 3.3 (5.2) | 1.2 (0–22.5) | 26 | 4.6 (9.8) | 0.7 (0–44.7) | 0.61 |
| 6 | 57 | 39 | 3.9 (5.7) | 2 (0–28.6) | 38 | 5.1 (11.7) | 1.6 (0–67.3) | 0.61 |
| 8 | 113 | 37 | 4.8 (9.5) | 1.7 (0–51.2) | 38 | 11.6 (36.6) | 1.5 (0–206.3) | 0.96 |
| 10 | 169 | 37 | 36.9 (84.1) | 7.2 (0–454.4) | 38 | 113.9 (228.8) | 9.5 (0–797.2) | 0.31 |
| 11 | 225 | 39 | 83 (85.3) | 65 (0–376.3) | 37 | 187.8 (269.2) | 70.5 (0–1176.3) | 0.38 |
| 12 | 281 | 39 | 182.5 (180.3) | 119.6 (0–715) | 34 | 310.7 (564.5) | 136.7 (1.3–3015) | 0.91 |
| 13 | 337 | 39 | 228.2 (162.8) | 207.2 (0–670.1) | 34 | 282.8 (322.4) | 182.6 (5–1258) | 0.80 |
| 14 | 393 | 36 | 278.3 (199.9) | 267.9 (12.6–881.3) | 32 | 379.5 (554.1) | 201.9 (0.6–2826.3) | 0.50 |
| 15 | 449 | 35 | 282.4 (185.9) | 273.5 (7.6–834.6) | 30 | 274 (291.7) | 190 (0–1191.3) | 0.28 |
| 16 | 505 | 35 | 276.6 (165.8) | 267.3 (8–575) | 29 | 253.2 (230) | 214 (0–856.5) | 0.19 |
min-max, minimum-maximum.