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a OS (any irAE vs. no irAE); (b): OS (grade ≥3 vs. grades 1–2 vs. no irAE); (c): PFS (any irAE vs. no irAE); (d): PFS (grade ≥3 vs. grades 1–2 vs. no irAE). irAE, immune-related adverse event; ICI, immune checkpoint inhibitor; OS, overall survival; PFS, progression-free survival.
