Table 4.

Interaction Models

	ηp2	Estimate [95% CI]	p
Sex*APOE4 a
Global PIB SUVR
Sex	.009	0.105 [−0.102, 0.313]	.32
APOE4	<.001	0.015 [−0.176, 0.207]	.87
Sex*APOE4	.001	0.044 [−0.223, 0.310]	.75
Temporal Meta-ROI FTP SUVR
Sex	.099	0.414 [0.176, 0.652]	<.001
APOE4	.027	0.193 [−0.028, 0.413]	.09
Sex*APOE4	.040	−0.330 [−0.636, −0.024]	.035
Entorhinal FTP SUVR
Sex	.10	0.272 [0.118, 0.425]	<.001
APOE4	.072	0.209 [0.067, 0.351]	.004
Sex*APOE4	.024	−0.165 [−0.362, 0.033]	.10
Sex*Age b
Global PIB SUVR
Sex	.043	0.146 [0.018, 0.273]	.025
Age	<.001	−0.001 [−0.011, 0.010]	.88
Age*Sex	.001	−0.002 [−0.016, 0.0118]	.77
Temporal Meta-ROI FTP SUVR
Sex	.070	0.221 [0.071, 0.370]	.004
Age	.083	−0.020 [−0.032, −0.008]	.002
Age*Sex	.004	0.006 [−0.011, 0.022]	.50
Sex*CDR-SoB c
Global PIB SUVR
Sex	.043	0.146 [0.019, 0.274]	.025
CDR-SoB	<.001	−0.002 [−0.039, 0.035]	.92
Sex*CDR-SoB	.004	0.020 [−0.040, 0.081]	.51
Temporal Meta-ROI FTP SUVR
Sex	.070	0.221 [0.072, 0.370]	.004
CDR-SoB	.132	0.054 [0.011, 0.098]	.015
Sex*CDR-SoB	.003	−0.021 [−0.092, 0.051]	.57

Reference levels are male and ε4 non-carrier for sex and APOE4 status, respectively. η_p²: partial eta-squared. CDR-SoB = Clinical Dementia Rating Sum of Boxes.

^aAPOE data available on 56 males and 59 females (total n=115). APOE4 is coded as either an ε4 carrier or non-carrier. Models controlled additionally for age and Clinical Dementia Rating Sum of Boxes.

^bModels controlled additionally for Clinical Dementia Rating Sum of Boxes.

^cModels controlled additionally for age.