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. Author manuscript; available in PMC: 2022 Feb 7.
Published in final edited form as: J Alzheimers Dis. 2022;85(2):627–644. doi: 10.3233/JAD-210455

Fig. 2.

Fig. 2.

Longitudinal change in global cognition by a) baseline dichotomous diagnosis (all diagnostic methods), b) consensus subtype, c) actuarial subtype, and d) LCA subtype. Each bracket/asterisk denotes a significant group difference (p < 0.05) in the slope of change in MMSE. For example, in (d), the HN, LN, and M groups differ significantly from the ML and ME groups in the slope of change in MMSE, and the ML and ME groups differ from one another in the slope of change in MMSE. MMSE, Mini-Mental State Examination; LCA, latent class analysis; NC, normal cognition; aMCI, amnestic mild cognitive impairment; naMCI, non-amnestic MCI; SD, single domain; MD, multi-domain; HN, high normal; LN, low normal; M, memory only; ML, memory/language; ME, memory/executive.