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. 2022 Jan 26:NEJMoa2116414. doi: 10.1056/NEJMoa2116414

Table 1. Characteristics of the Participants at Enrollment.*.

Characteristic mRNA-1273 Booster Ad26.COV2.S Booster BNT162b2 Booster
Primary Ad26.COV2.S Primary mRNA-1273 Primary BNT162b2 Primary Ad26.COV2.S Primary mRNA-1273 Primary BNT162b2 Primary Ad26.COV2.S Primary mRNA-1273 Primary BNT162b2
Group no. 1 2 3 4 5 6 7 8 9
No. of participants 53 51 50 50 49 51 53 51 50
Sex — no. (%)
Female 26 (49) 32 (63) 29 (58) 27 (54) 16 (33) 23 (45) 29 (55) 26 (51) 23 (46)
Male 27 (51) 19 (37) 21 (42) 23 (46) 33 (67) 28 (55) 24 (45) 25 (49) 27 (54)
Age — yr
Mean 57±14 53±16 55±17 50±14 50±17 50±15 48±14 54±17 50±18
Range 24–81 24–76 22–85 24–77 20–75 20–76 22–74 23–75 19–80
Race and ethnic group — no. (%)
Asian 4 (8) 5 (10) 4 (8) 3 (6) 5 (10) 6 (12) 1 (2) 2 (4) 1 (2)
Hawaiian or Pacific Islander 0 0 0 0 0 0 1 (2) 0 0
Black 1 (2) 2 (4) 3 (6) 0 0 2 (4) 0 2 (4) 1 (2)
White 46 (87) 41 (80) 43 (86) 44 (88) 43 (88) 40 (78) 50 (94) 47 (92) 43 (86)
Multiracial 1 (2) 3 (6) 0 3 (6) 1 (2) 2 (4) 1 (2) 0 4 (8)
Hispanic or Latino 4 (8) 4 (8) 3 (6) 2 (4) 0 3 (6) 2 (4) 2 (4) 5 (10)
Other 1 (2) 0 0 0 0 1 (2) 0 0 1 (2)
Ethnic group not reported 0 1 (2) 0 1 (2) 0 0 0 0 0
Interval between first and second primary doses — days
Mean NA 29±3 23±8 NA 28±3 22±3 NA 28±2 22±5
Range NA 24–40 16–71 NA 19–36 18–42 NA 24–32 11–46
Interval between second dose and booster — wk§
Mean 14±1 16±2 17±2 18±2 19±4 21±6 20±2 23±5 24±5
Range 12–16 12–20 12–21 14–21 13–26 12–41 11–23 13–29 14–32
*

Plus–minus values are means ±SD. NA denotes not applicable because these participants received a single dose.

Listed in this group is one participant who withdrew from the trial during the day 1 visit and did not receive a booster vaccination.

Race and ethnic group were reported by the participant and were collected as two categories, so percentages in each category do not total 100%.

§

For the participants who received the one-dose Ad26.COV2.S primary vaccine, data are listed for the interval after the single dose.