Table 1. Characteristics of the Participants at Enrollment.*.
Characteristic | mRNA-1273 Booster | Ad26.COV2.S Booster | BNT162b2 Booster | ||||||
---|---|---|---|---|---|---|---|---|---|
Primary Ad26.COV2.S | Primary mRNA-1273 | Primary BNT162b2 | Primary Ad26.COV2.S | Primary mRNA-1273 | Primary BNT162b2 | Primary Ad26.COV2.S | Primary mRNA-1273 | Primary BNT162b2 | |
Group no. | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 |
No. of participants | 53 | 51 | 50 | 50 | 49 | 51 | 53† | 51 | 50 |
Sex — no. (%) | |||||||||
Female | 26 (49) | 32 (63) | 29 (58) | 27 (54) | 16 (33) | 23 (45) | 29 (55) | 26 (51) | 23 (46) |
Male | 27 (51) | 19 (37) | 21 (42) | 23 (46) | 33 (67) | 28 (55) | 24 (45) | 25 (49) | 27 (54) |
Age — yr | |||||||||
Mean | 57±14 | 53±16 | 55±17 | 50±14 | 50±17 | 50±15 | 48±14 | 54±17 | 50±18 |
Range | 24–81 | 24–76 | 22–85 | 24–77 | 20–75 | 20–76 | 22–74 | 23–75 | 19–80 |
Race and ethnic group — no. (%)‡ | |||||||||
Asian | 4 (8) | 5 (10) | 4 (8) | 3 (6) | 5 (10) | 6 (12) | 1 (2) | 2 (4) | 1 (2) |
Hawaiian or Pacific Islander | 0 | 0 | 0 | 0 | 0 | 0 | 1 (2) | 0 | 0 |
Black | 1 (2) | 2 (4) | 3 (6) | 0 | 0 | 2 (4) | 0 | 2 (4) | 1 (2) |
White | 46 (87) | 41 (80) | 43 (86) | 44 (88) | 43 (88) | 40 (78) | 50 (94) | 47 (92) | 43 (86) |
Multiracial | 1 (2) | 3 (6) | 0 | 3 (6) | 1 (2) | 2 (4) | 1 (2) | 0 | 4 (8) |
Hispanic or Latino | 4 (8) | 4 (8) | 3 (6) | 2 (4) | 0 | 3 (6) | 2 (4) | 2 (4) | 5 (10) |
Other | 1 (2) | 0 | 0 | 0 | 0 | 1 (2) | 0 | 0 | 1 (2) |
Ethnic group not reported | 0 | 1 (2) | 0 | 1 (2) | 0 | 0 | 0 | 0 | 0 |
Interval between first and second primary doses — days | |||||||||
Mean | NA | 29±3 | 23±8 | NA | 28±3 | 22±3 | NA | 28±2 | 22±5 |
Range | NA | 24–40 | 16–71 | NA | 19–36 | 18–42 | NA | 24–32 | 11–46 |
Interval between second dose and booster — wk§ | |||||||||
Mean | 14±1 | 16±2 | 17±2 | 18±2 | 19±4 | 21±6 | 20±2 | 23±5 | 24±5 |
Range | 12–16 | 12–20 | 12–21 | 14–21 | 13–26 | 12–41 | 11–23 | 13–29 | 14–32 |
Plus–minus values are means ±SD. NA denotes not applicable because these participants received a single dose.
Listed in this group is one participant who withdrew from the trial during the day 1 visit and did not receive a booster vaccination.
Race and ethnic group were reported by the participant and were collected as two categories, so percentages in each category do not total 100%.
For the participants who received the one-dose Ad26.COV2.S primary vaccine, data are listed for the interval after the single dose.