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. Author manuscript; available in PMC: 2022 Jul 5.
Published in final edited form as: Nat Chem. 2022 Jan 5;14(1):94–99. doi: 10.1038/s41557-021-00834-8

Fig. 1 |. Common strategies for decarboxylative coupling usually involve prefunctionalizations of either or both reacting partners while the current strategy enables direct decarboxylative coupling.

Fig. 1 |

a, Redox-neutral cross-couplings of carboxylic acid feedstocks. b, Use of redox-active PINO and iodinane esters for formal decarboxylative coupling reactions. c, Proposed design plan for oxidative decarboxylative cross-couplings employing visible-light photoactive Cu(II) carboxylates.