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. 2022 Jan 24;14:819440. doi: 10.3389/fnmol.2021.819440

FIGURE 1.

FIGURE 1

The CSDS model induces depression-like behaviors and increases cerebral glycogen levels. (A) Schema of the experimental design. Experimental timeline of the 10-day CSDS protocol, behavioral tests, and medial prefrontal cortex tissue collection. (B) CSDS induced depression-like behaviors as assessed by social interaction (n = 9), (C) sucrose preference (n = 9), and (D) tail suspension (n = 9) tests. (E) Glycogen expression significantly increased after various attack times (n = 5). *p < 0.05, **p < 0.01, ****p < 0.0001. CTRL, control mouse models; SS, stress-susceptible mouse models.