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. 2022 Feb 3;15:297–305. doi: 10.2147/DMSO.S351973

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© 2022 Qi et al.

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Sleeve gastrectomy (SG) alleviates obesity and glucose metabolic disorders in obese and T2D model. (A) Illustration of sham, antrum preservation SG (AP-SG) and antrum resection SG (AR-SG) operation. The resection line started 1 cm from the pyloric ring (yellow arrow). The resection line started as close as possible near the gastroduodenal junction (green arrow). D = duodenum; A = antrum; S = stomach. (B) Eight weeks after operation, representative appearances of mice in sham, AP-SG and AR-SG group are recorded. Illustrates changes in body weight (C), food intake (D), fasting glucose level (E) after operation. Oral glucose tolerance test (OGTT) results preoperative (F) and postoperatively (G), and area under the curve (AUC) for glucose level (H) are presented. Data (n = 8) are shown as mean ± SD. *Significant AP-SG compared with sham (P < 0.05). ^{^}Significant AR-SG compared with sham (P < 0.05). ^#Significant AR-SG compared with AP-SG. ^aP< 0.05.