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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: J Hypertens. 2022 Mar 1;40(3):498–511. doi: 10.1097/HJH.0000000000003038

Figure 4:

Figure 4:

A) Systolic blood pressure during 12 days of AAA treatment of WT and Myh11-4a12 mice. Number of mice in each group is in parenthesis. Results are means ± SE, ****p<0.0001 vs vehicle-treated Myh11-4a12 (2-way ANOVA repeated measures). B) Phenylephrine-induced contraction dose-response (N=7, WT; N=9, Myh11-4a12; N=6, Myh11-4a12 + AAA). Results are means ± SE, ***p<0.001 vs WT; ##p<0.01 vs Myh11-4a12 (one-way ANOVA). C) Acetylcholine-induced relaxation dose-response (N=7 mice/group). Results are means ± SE, ***p<0.001 vs WT; ###p<0.001 vs vehicle-treated Myh11-4a12 mice (one-way ANOVA). D) Media to lumen ratio, E) media thickness, and F) media cross-sectional area (N=6-9/group). Results are means ± SE; *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 (one-way ANOVA).