Table 1.
Comparison of Baseline Characteristics Between Study Arms (N = 146)
| Characteristics | Short-storage RBC arm | Standard-issue RBC arm | p-value |
|---|---|---|---|
| N = 69 | N = 77 | ||
| Age at admission (years) (mean, SD) | 5.2 ± 5.2 | 5.4 ± 4.9 | 0.81 |
| Hemoglobin prior to transfusion (g/dl) (mean,SD) | 6.9 ± 0.9 | 7.0 ± 1.4 | 0.27 |
| Sex (n,%) | 0.62 | ||
| Female | 39 (56.5) | 40 (51.9) | |
| Male | 30 (43.5) | 37 (48.1) | |
| Type of ICU admission (n,%) | 0.56 | ||
| General medical | 55 (79.7) | 56 (72.7) | |
| Cardiac | 0 | 3 (3.9) | |
| Surgical | 7 (10.1) | 12 (15.6) | |
| Trauma | 7 (10.1) | 6 (7.8) | |
| Time from admission to transfusion (days) (mean, SD) | 2.16 (1.5) | 2.17 (1.6) |
0.97 |
| PELOD-2 Score at randomization (mean, SD) | 5.7 (2.9) | 4.8 (2.9) | 0.06 |
| Opiate exposure (n,%) | 52 (75.4%) | 46 (59.7%) | 0.04 |
| Benzodiazepine exposure (n,%) | 42 (60.9%) | 32 (41.6%) | 0.02 |
SD: standard deviation; IQR: interquartile range; MODS: multiple organ dysfunction syndrome; PELOD-2: Pediatric Logistic Organ Dysfunction-2 score; RBC: red blood cell.