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. 2021 Sep 10;70(5):799–808. doi: 10.33549/physiolres.934665

Supplementary Table 2.

Correlation of selected inflammatory parameters and PCDAI with fatty acid composition of plasma lipid classes.

Fatty acid a Phospholipids Triacylglycerols Cholesteryl esters
FC CRP PCDAI FC CRP PCDAI FC CRP PCDAI
14:0 0.234 −0.189 0.128 0.362 −0.147 0.175 0.067 −0.182 −0.105
16:0 0.115 −0.118 0.429 0.438* −0.383 −0.002 0.008 0.135 0.071
16:1n−9 0.165 0.372 0.031 −0.183 0.035 0.100 −0.040 −0.227 −0.218
16:1n−7 0.283 0.041 −0.152 −0.034 0.107 −0.112 −0.029 −0.001 −0.117
18:0 −0.001 0.108 0.226 0.124 0.122 0.318 0.005 0.016 −0.030
18:1n−9 0.291 0.387 0.644** −0.054 0.447 0.289 0.057 0.280 0.211
18:1n−7 0.168 0.257 0.225 0.064 −0.217 −0.291 −0.033 0.425 0.091
18:2n−6 0.067 −0.094 −0.118 −0.322 −0.189 −0.418 −0.075 −0.369 −0.278
18:3n−6 0.282 0.045 0.111 −0.049 −0.140 −0.209 0.126 −0.043 0.085
18:3n−3 0.262 0.029 0.038 0.054 −0.164 −0.274 0.228 −0.004 0.100
20:2n−6 0.157 −0.225 0.174 −0.161 −0.003 0.070 −0.357 −0.341 −0.210
20:3n−6 −0.101 −0.260 −0.282 −0.363 −0.031 −0.356 −0.113 −0.095 −0.125
20:4n6 −0.367 −0.014 −0.258 −0.623** 0.003 −0.248 0.068 0.155 0.270
20:5n3 −0.052 −0.142 −0.477 −0.189 0.054 −0.409 0.254 0.109 0.273
22:4n6 0.119 −0.027 −0.029 −0.364 0.072 −0.346 −0.321 −0.408 −0.358
22:5n6 0.279 −0.271 −0.253 −0.365 −0.171 −0.644** −0.273 −0.353 −0.323
22:5n3 0.144 0.112 −0.138 −0.296 0.132 −0.385 −0.244 −0.202 −0.241
22:6n3 0.063 0.024 −0.369 −0.160 −0.088 −0.584** −0.198 −0.173 −0.115
∑satur 0.045 0.160 0.339 0.427* −0.312 0.103 0.012 0.103 0.050
∑mono 0.412 0.424* 0.661** −0.010 0.440 0.287 0.019 0.254 0.156
∑n6 −0.338 −0.317 −0.459 −0.448* −0.164 −0.453 −0.015 −0.221 −0.118
∑n3 0.062 0.056 −0.378 −0.229 −0.128 −0.618** 0.282 0.059 0.136
∑n6/∑n3 −0.111 −0.174 0.275 0.004 0.103 0.471 −0.335 −0.168 −0.230

Only Crohn’s disease (CD) group. Spearman rank correlation coefficients:

*

p<0.05,

**

p<0.01,

***

p<0.001.

∑ – Sum,

a

– shorthand notation of fatty acids-number before colon=number of double bonds; number after n=number of carbon atoms from the methyl end of the chain to the nearest double bond.

CRP – C-reactive protein, FC – fecal calprotectin, PCDAI – Paediatric Crohn’s Disease Activity Index.