Table 1.
Basic laboratory characteristics of the study groups
| Parameter | Patients | Healthy Controls | p value |
|---|---|---|---|
| Number | 25 | 21 | |
| Age (years) | 72 (55–79) | 41 (30–53) | <0.0001 |
| Protein (g/l) | 69 (66–71) | 72 (67–74) | ns |
| CRP (mg/l) | 1.8 (1.0–4.1) | 3.1 (1.5–4.3) | ns |
| ALT (μkat/l) | 0.34 (0.28–0.49) | 0.40 (0.31–0.48) | ns |
| AST (μkat/l) | 0.42 (0.36–0.48) | 0.37 (0.30–0.45) | ns |
| GGT (μkat/l) | 0.43 (0.3–1.0) | 0.36 (0.30–0.56) | ns |
| Urea (mmol/l) | 6.2 (4.9–7.2) | 4.9 (3.9–6.4) | ns |
| Creatinine (μmol/l) | 84 (78–97) | 65 (58–77) | ns |
| Hemoglobin (g/l) | 147 (142–154) | 135 (131–151) | 0.026 |
| Leukocytes (x10 9 /l) | 6.5 (4.8–8.2) | 6.5 (5.7–8.4) | ns |
| Thrombocytes (x10 9 /l) | 214 (178–252) | 243 (204–305) | ns |
All data shown as median (interquartile range). Abbreviations: CRP – C-reactive protein, ALT – Alanine aminotransferase, AST – Aspartate aminotransferase, GGT – Gamma-glutamyltransferase. All results were considered statistically significant at p<0.05, ns, not significant.