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. 2022 Feb 7;17(2):e0263536. doi: 10.1371/journal.pone.0263536

Fig 5. Regulatory T cells in JSLE patients, stratified into treatment-naïve and treated groups during 6-months follow-up.

Fig 5

(A, B) Percentages of Tregs (A) and SLEDAI-2K (B) at 0, 3, and 6 months of follow-up in 49 JSLE patients. Horizontal lines represent medians and interquartile ranges. The horizontal dashed lines in (A) illustrate the medians in healthy controls. The dashed lines in (B) represent individual treatment-naïve patients, and solid lines in (B) represent individual treated patients. Total JSLE patients (treatment-naïve patients = 18, treated patients = 31), non-LN JSLE patients (treatment-naïve patients = 13, treated patients = 19), LN JSLE patients (treatment-naïve patients = 5, treated patients = 12). JSLE, juvenile-onset systemic lupus erythematosus; LN, lupus nephritis; Tregs, regulatory T cells; N, treatment-naïve patients; T, treated patients; SLEDAI-2K, systemic lupus erythematosus disease activity index 2000.