Table 2.

Molecular docking details of isolated compounds 1 and 2 and against urease and tyrosinase enzymes.

Compound		Hydrogen bonding residues and distance		Hydrophobic interacting residues	B. affinity (kcal/mol)
1		His541	3.32 Å	His408, Cys442, Leu488, His491, Ile517 and Tyr543	–8.7
2		Ala439	2.69 Å	Cys405, His408, Thr437, Cys442, Leu488, His491, Ile517, His541 and Tyr543	–8.7
Thiourea (standard)					–3.4
1	No H bonding			Gly62, Phe90, Trp93, Val262, Phe292 and His296	–7.6
2	No H bonding			Phe90, Val262, Phe292, His295 and His296	–7.5
Kojic acid (standard)					–5.1