Table 4.
Reported symptoms at 3 months by SARS-CoV-2 status, overall and stratified by age group
|
All participants |
Participants aged 11–14 years |
Participants aged 15–17 years |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Tested positive for SARS-CoV-2 (n=3065) | Tested negative for SARS-CoV-2 (n=3739) | p value* | Tested positive for SARS-CoV-2 (n=1244) | Tested negative for SARS-CoV-2 (n=1609) | p value* | Tested positive for SARS-CoV-2 (n=1821) | Tested negative for SARS-CoV-2 (n=2130) | p value* | ||
| No reported symptoms | 1027 (33·5%) | 1746 (46·7%) | <0·0001 | 492 (39·5%) | 845 (52·5%) | <0·0001 | 535 (29·4%) | 901 (42·3%) | <0·0001 | |
| 1 symptom | 671 (21·9%) | 1019 (27·3%) | .. | 293 (23·6%) | 436 (27·1%) | .. | 378 (20·8%) | 583 (27·4%) | .. | |
| 2 symptoms | 439 (14·3%) | 371 (9·9%) | .. | 167 (13·4%) | 123 (7·6%) | .. | 272 (14·9%) | 248 (11·6%) | .. | |
| 3 symptoms | 300 (9·8%) | 228 (6·1%) | .. | 91 (7·3%) | 68 (4·2%) | .. | 209 (11·5%) | 160 (7·5%) | .. | |
| 4 symptoms | 217 (7·1%) | 137 (3·7%) | .. | 70 (5·6%) | 51 (3·2%) | .. | 147 (8·1%) | 86 (4·0%) | .. | |
| ≥5 symptoms | 411 (13·4%) | 238 (6·4%) | .. | 131 (10·5%) | 86 (5·3%) | .. | 280 (15·4%) | 152 (7·1%) | .. | |
| Specific symptoms | ||||||||||
| Fever | 50 (1·6%) | 55 (1·5%) | 0·59 | 9 (0·7%) | 18 (1·1%) | 0·28 | 41 (2·3%) | 37 (1·7%) | 0·25 | |
| Chills | 269 (8·8%) | 192 (5·1%) | <0·0001 | 96 (7·7%) | 88 (5·5%) | 0·015 | 173 (9·5%) | 104 (4·9%) | <0·0001 | |
| Persistent cough | 98 (3·2%) | 98 (2·6%) | 0·16 | 35 (2·8%) | 41 (2·5%) | 0·66 | 63 (3·5%) | 57 (2·7%) | 0·15 | |
| Tiredness | 1196 (39·0%) | 911 (24·4%) | <0·0001 | 378 (30·4%) | 277 (17·2%) | <0·0001 | 818 (44·9%) | 634 (29·8%) | <0·0001 | |
| Shortness of breath | 717 (23·4%) | 388 (10·4%) | <0·0001 | 202 (16·2%) | 135 (8·4%) | <0·0001 | 515 (28·3%) | 253 (11·9%) | <0·0001 | |
| Loss of smell | 414 (13·5%) | 51 (1·4%) | <0·0001 | 145 (11·7%) | 12 (0·7%) | <0·0001 | 269 (14·8%) | 39 (1·8%) | <0·0001 | |
| Unusually hoarse voice | 56 (1·8%) | 46 (1·2%) | 0·044 | 21 (1·7%) | 20 (1·2%) | 0·32 | 35 (1·9%) | 26 (1·2%) | 0·075 | |
| Unusual chest pain | 216 (7·0%) | 129 (3·5%) | <0·0001 | 61 (4·9%) | 46 (2·9%) | 0·0044 | 155 (8·5%) | 83 (3·9%) | <0·0001 | |
| Unusual abdominal pain | 119 (3·9%) | 107 (2·9%) | 0·019 | 43 (3·5%) | 33 (2·1%) | 0·021 | 76 (4·2%) | 74 (3·5%) | 0·25 | |
| Diarrhoea | 92 (3·0%) | 80 (2·1%) | 0·024 | 35 (2·8%) | 29 (1·8%) | 0·071 | 57 (3·1%) | 51 (2·4%) | 0·16 | |
| Headaches | 710 (23·2%) | 530 (14·2%) | <0·0001 | 258 (20·7%) | 174 (10·8%) | <0·0001 | 452 (24·8%) | 356 (16·7%) | <0·0001 | |
| Confusion, disorientation, or drowsiness | 198 (6·5%) | 123 (3·3%) | <0·0001 | 61 (4·9%) | 43 (2·7%) | 0·0016 | 137 (7·5%) | 80 (3·8%) | <0·0001 | |
| Unusual eye-soreness | 182 (5·9%) | 134 (3·6%) | <0·0001 | 55 (4·4%) | 49 (3·0%) | 0·052 | 127 (7·0%) | 85 (4·0%) | <0·0001 | |
| Skipping meals | 296 (9·7%) | 275 (7·4%) | 0·0007 | 84 (6·8%) | 91 (5·7%) | 0·23 | 212 (11·6%) | 184 (8·6%) | 0·0017 | |
| Dizziness or light-headedness | 419 (13·7%) | 314 (8·4%) | <0·0001 | 123 (9·9%) | 104 (6·5%) | 0·0008 | 296 (16·3%) | 210 (9·9%) | <0·0001 | |
| Sore throat | 291 (9·5%) | 281 (7·5%) | 0·0034 | 129 (10·4%) | 107 (6·7%) | 0·0004 | 162 (8·9%) | 174 (8·2%) | 0·41 | |
| Unusually strong muscle pains | 165 (5·4%) | 83 (2·2%) | <0·0001 | 56 (4·5%) | 29 (1·8%) | <0·0001 | 109 (6·0%) | 54 (2·5%) | <0·0001 | |
| Earache or ringing in ears | 191 (6·2%) | 165 (4·4%) | 0·0008 | 72 (5·8%) | 71 (4·4%) | 0·10 | 119 (6·5%) | 94 (4·4%) | 0·0032 | |
| Raised welts on skin or swelling | 48 (1·6%) | 32 (0·9%) | 0·0069 | 22 (1·8%) | 15 (0·9%) | 0·050 | 26 (1·4%) | 17 (0·8%) | 0·057 | |
| Red or purple sores or blisters on feet | 35 (1·1%) | 40 (1·1%) | 0·78 | 14 (1·1%) | 17 (1·1%) | 0·86 | 21 (1·2%) | 23 (1·1%) | 0·83 | |
| Other | 335 (10·9%) | 590 (15·8%) | <0·0001 | 145 (11·7%) | 280 (17·4%) | <0·0001 | 190 (10·4%) | 310 (14·6%) | 0·0001 | |
*
p values need to be considered after correcting for multiple testing using a Bonferroni adjustment (number of tests=66; ie, p<0·05 corresponds to p<0·000758 and p<0·01 corresponds to p<0·000152).