Table 4.
Multivariable regression analysis for red blood cell transfusion
| Generalized estimating equations (group variable: hospital code) | Multivariable analysis |
|
|---|---|---|
| RR (95% CI) | P value | |
| Diabetes mellitus | 2.44 (2.01–2.96) | <0.001 |
| Age, yr | 1.04 (1.03–1.05) | <0.001 |
| Female, sex | 1.63 (1.38–1.93) | <0.001 |
| BMI (kg/m2) | See Figure 3 | |
| Main diagnosis | ||
| AKI or RPGN | 3.92 (3.20–4.80) | <0.001 |
| Nephrosis | 0.86 (0.66–1.11) | 0.23 |
| Others | 1 (base) | |
| Presence of CKD | 2.70 (2.26–3.22) | <0.001 |
| Hospital volume | ||
| 1–24/yr | 1 (base) | |
| 25–44/yr | 0.82 (0.66–1.00) | 0.055 |
| ≥45/yr | 0.83 (0.67–1.03) | 0.09 |
| Academic hospital | 1.43 (1.16–1.76) | 0.001 |
| Fiscal year period | 0.17 | |
| 2010–2015 | 1 (base) | |
| 2016–2017 | 0.88 (0.74–1.05) | |
| ADL | <0.001 | |
| Dependent | 2.64 (2.06-3.37) | |
| Independent | 1 (base) | |
| Corticosteroid use | 1.41 (1.03–1.92) | 0.032 |
| Immunosuppressant use | 0.93 (0.37–2.35) | 0.88 |
| Antithrombotic use | 1.03 (0.66–1.62) | 0.89 |
ADL, activities of daily living; AKI, acute kidney injury; BMI, body mass index; CKD, chronic kidney disease; RPGN, rapidly progressive glomerulonephritis; RR, relative risk.
BMI calculated as weight in kilograms divided by the square of height in meters.