Table 1.
Association of NLRC4 (c.478G > A, p.A160T) with ulcerative colitis (UC) in the genome across different populations. Data accessed from IBD Exomes Portal, Cambridge, MA http://ibd.broadinstitute.org, accessed October 2018
| Population | Homozygous reference | Heterozygous alternate | UC allele frequency | Non-UC allele frequency | OR [95% interval] | P-value |
|---|---|---|---|---|---|---|
| European (Ashkenazi-Jewish) | 5680 | 5 | 0.0007184 | 0.0003292 | 1.035 | 0.9749 |
| Non-Finnish European | 7726 | 14 | 0.001161 | 0.000361 | 2.862 | 0.1707 |
| European (Finnish) | 11,453 | 26 | 0.003589 | 0.001159 | 4.125 | 0.0392 |
| Total |
2.546 [1.778, 3.644] |
0.01305 |