Fig. 3.

Scatterplots of enriched KEGG pathways for combined lipidomic/metabolomic experiments when comparing Pex11α knockout (KO; Pex11α^−/−) with wild type (WT; Pex11α^+/+) control mice. Pathway topology analysis depicting the dysregulated metabolic pathways in a serum, b liver, and c heart tissue homogenates, respectively. Here, the x-axis represents the pathway impact, and the y-axis represents the pathway enrichment. Each node marks a pathway. The size (pathway impact value) and color (-log10 p-value) of the nodes represent the number of lipid/polar metabolite species and level of significance, respectively