Table 1.
Oral (n = 1509) | Infusible (n = 495) | p-Values | |||
---|---|---|---|---|---|
n or mean | % or SD | n or mean | % or SD | ||
Disease duration (years, SD) | 10.1 | 6.5 | 10.7 | 6.9 | 0.215 |
Age (years, SD) | 42.5 | 11.6 | 38.6 | 11.5 | <0.001 |
Gender—Female | 370 | 72.7% | 378 | 76.4% | 0.182 |
Previous DMT* | <0.001 | ||||
Interferons | 74 | 14.5% | 84 | 17.0% | |
Glatiramer acetate | 137 | 26.9% | 150 | 30.3% | |
Natalizumab | 145 | 28.5% | 60 | 12.1% | |
Rituximab | 6 | 1.2% | 0 | 0.0% | |
Fingolimod | 17 | 3.3% | 23 | 4.7% | |
Dimethyl fumarate | 1 | 0.2% | 2 | 0.4% | |
None | 121 | 23.8% | 165 | 33.3% | |
Other | 8 | 1.6% | 11 | 2.1% | |
Contrast enhancement on baseline MRI | 90 | 20.4% | 143 | 34.1% | <0.001 |
Disease burden on baseline MRI | 0.629 | ||||
Mild | 232 | 45.6% | 208 | 42.0% | |
Moderate | 141 | 27.7% | 152 | 30.7% | |
Severe | 53 | 10.4% | 49 | 9.9% | |
Missing | 83 | 16.3% | 86 | 17.4% |
DMT, disease modifying therapy; SD, standard deviation; n, sample size.
Within 6 months prior to starting study drug.