Table 2:
Bivariate and multivariate analysis of characteristics associated with high-risk HPV (hrHPV) detection on home self-collection in under-screened women in North Carolina.
| Characteristics | Total | hrHPV pos n (% positive) | Crude OR (95% CI) | Adjusted OR (95% CI)* |
|---|---|---|---|---|
| Total | 329† | 52 (16%)§§ | - | - |
|
| ||||
| Age | ||||
| 24-34 years | 91 | 17 (19%) | 1.38 (0.64-3.00) | - |
| 35-49 years | 142 | 21 (15%) | 1.03 (0.50-2.14) | - |
| 50-65 years | 97 | 14 (14%) | REF | - |
| Time since last Pap smear (years)‡ | ||||
| 4-5 years ago | 157 | 23 (15%) | REF | - |
| 6 or more years ago / Never had a Pap | 151 | 28 (19%) | 1.31 (0.72-2.41) | - |
| Don’t know | 22 | 1 (5%) | - | - |
| Has a history of abnormal Pap smear(s)‡ | ||||
| No | 167 | 25 (15%) | REF | - |
| Yes | 135 | 22 (16%) | 1.12 (0.60-2.08) | - |
| Don’t know | 2 | 1 (50%) | - | - |
| Health insurance | ||||
| Insured (Medicaid/Medicare) | 70 | 13 (19%) | REF | - |
| Uninsured | 260 | 39 (15%) | 1.23 (0.64-2.57) | - |
| Income, annual household | ||||
| $0-$9,999 | 103 | 22 (21%) | 2.32(1.01-5.36) | 1.93 (0.82-4.56) |
| $10,000-$24,999 | 126 | 20 (16%) | 1.61 (0.70-3.74) | 1.59 (0.67-3.63) |
| ≥$25,000 | 87 | 9 (10%) | REF | REF |
| Race/ethnicity§ | ||||
| Non-Hispanic white | 143 | 20 (40%) | REF | - |
| Non-Hispanic black | 152 | 25 (16%) | 1.22 (0.64-2.31) | - |
| Hispanic | 13 | 2 (15%) | 1.12 (0.23-5.42) | - |
| Other** | 18 | 5 (28%) | 2.37 (0.76-7.36) | - |
| Marital status | ||||
| Married or living with partner | 81 | 11 (14%) | REF | - |
| Single or never married | 154 | 24 (16%) | 1.18 (0.56-2.56) | - |
| Divorced, separated or widowed | 92 | 17 (18%) | 1.44 (0.63-3.29) | - |
| Sexual orientation | ||||
| Heterosexual | 300 | 47 (16%) | REF | - |
| Gay/Lesbian or Bisexual | 28 | 5 (18%) | 1.17 (0.42-3.22) | - |
| Age of first sexual intercourse | ||||
| Never had sex | 2 | 0 | - | - |
| <16 years | 126 | 18 (14%) | REF | - |
| ≥16 years | 199 | 33 (17%) | 1.20 (0.64-2.24) | - |
| Number of sexual partners in the last year | ||||
| Never had sex | 2 | 0 | - | - |
| 0-1 partner | 250 | 33 (13%) | REF | REF |
| 2 or more partners | 74 | 18 (24%) | 2.15 (1.13-4.11) | 2.00 (1.03-3.88) |
| Current smoking | ||||
| Non-smoker | 189 | 24 (13%) | REF | - |
| Smoker | 137 | 28 (20%) | 1.78 (0.98-3.23) | - |
Adjusted for Income, annual household and number of sexual partners in the last year
Totals may not add up to full sample size due to missing data
26 reported not having had a Pap smear in the past
Hispanic identification based on participant response to question “are you Hispanic or Latina?” Followed by “what is your race or ethnicity?” with self-classification options for “White,” “Black or African American” etc
Other races include those who identified as Asian (n=3), American Indian or Alaska Native (n=3) and more than one of the following: American Indian, Asian, Pacific Islander, black/African American and White (n=12).
Prevalence of HPV type 16 was 1.2% (n=4), HPV type 18/45 was 1.5% (n=5) and hrHPV non-16/18/45 was 13% (n=42). 1 invalid genotyping result