Table 6.
Aripiprazole | Brexpiprazole | Cariprazine | |
---|---|---|---|
Akathisia | + | +/– | + |
EPS | + | + | + |
Anxiety | ++ | + | + |
Sedation | + | +/– | +/– |
Weight gain | + | ++ | + |
Metabolic effects | + | + | + |
Hyperprolactinemia | +/– | + | +/– |
Nausea/vomiting | + | +/– | + |
Insomnia | + | +/– | +/– |
Impulse control symptoms/compulsive behaviors | + | +/– | +/– |
QTc prolongation | + | + | + |
Postural hypotension | + | + | + |
EPS, extrapyramidal symptoms; +/-, very low; +, low; ++, moderate.