Table 6.
Relative risk of the common side effects induced by DRPAs (modified from 4, 76).
| Aripiprazole | Brexpiprazole | Cariprazine | |
|---|---|---|---|
| Akathisia | + | +/– | + |
| EPS | + | + | + |
| Anxiety | ++ | + | + |
| Sedation | + | +/– | +/– |
| Weight gain | + | ++ | + |
| Metabolic effects | + | + | + |
| Hyperprolactinemia | +/– | + | +/– |
| Nausea/vomiting | + | +/– | + |
| Insomnia | + | +/– | +/– |
| Impulse control symptoms/compulsive behaviors | + | +/– | +/– |
| QTc prolongation | + | + | + |
| Postural hypotension | + | + | + |
EPS, extrapyramidal symptoms; +/-, very low; +, low; ++, moderate.