TABLE 1.
Performance of the KY493 screening probe and KY166 genus-specific probe relative to culture in the detection of mycobacteria in respiratory specimens
| Probe, specimen type, and test result | No. of specimens with the following culture result:
|
Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|
| Positive | Negative | |||
| KY493 | ||||
| All specimens | 89.0 | 93.9 | ||
| Positive | 154 | 43 | ||
| Negative | 19 | 661 | ||
| Smear-positive specimens | 95.2 | 100.0 | ||
| Positive | 119 | 0 | ||
| Negative | 6 | 3 | ||
| Smear-negative specimens | 72.9 | 93.9 | ||
| Positive | 35 | 43 | ||
| Negative | 13 | 658 | ||
| KY166 | ||||
| All specimens | 89.6 | 84.8 | ||
| Positive | 155 | 107 | ||
| Negative | 18 | 597 | ||
| Smear-positive specimens | 96.0 | 99.9 | ||
| Positive | 120 | 2a | ||
| Negative | 5 | 1 | ||
| Smear-negative specimens | 72.9 | 85.0 | ||
| Positive | 35 | 105 | ||
| Negative | 13 | 596 | ||
a
Corrected specificity. One specimen was smear and KY166 positive due to bronchoscope contamination.