Table 1.
The association between RNF135 promoter methylation level and clinical characteristics of patients with HCC from the TCGA.
| Low methylation | High methylation | ||||
|---|---|---|---|---|---|
| Variable | n | % | n | % | P-value |
| Sex | |||||
| Male | 129 | 52.40% | 117 | 47.60% | 0.157 |
| Female | 53 | 44.50% | 66 | 55.50% | |
| Age | |||||
| <60 | 85 | 49.10% | 88 | 50.90% | 0.791 |
| ≥60 | 97 | 50.50% | 95 | 49.50% | |
| Family history of cancer | |||||
| No | 109 | 47.20% | 122 | 52.80% | 0.051 |
| Yes | 72 | 58.10% | 52 | 41.90% | |
| HBV/HCV infection | |||||
| No | 115 | 55.80% | 91 | 44.20% | 0.011 |
| Yes | 66 | 42.30% | 90 | 57.70% | |
| Alcohol consumption | |||||
| No | 117 | 48.50% | 124 | 51.50% | 0.435 |
| Yes | 64 | 52.90% | 57 | 47.10% | |
| Tumor stage | |||||
| I & II | 134 | 49.30% | 138 | 50.70% | 0.832 |
| III & IV | 46 | 50.50% | 45 | 49.50% | |
| Vascular invasion | |||||
| No | 123 | 51.50% | 116 | 48.50% | 0.281 |
| Yes | 55 | 45.50% | 66 | 54.50% | |
| Recurrence/Progression | |||||
| No | 64 | 43.20% | 84 | 56.80% | 0.018 |
| Yes | 94 | 56.60% | 72 | 43.40% | |
Bold values represent significant differences.