Figure 3.

IATL increases the cytotoxicity of DOX in HCT116 and HCT-15 cells. (A, B) Cell viability was measured in HCT116 and HCT-15 cells after treated with IATL or DOX alone or their combination for 24 h. (C, D) Combination index (CI) values were calculated using the Chou-Talalay method. (E–G) The number of colonies were assessed after treated with IATL or DOX alone or their combination. (H) Cell morphology was observed after treated with IATL or DOX alone or their combination. Scale bar = 25 µm. Data from three technical replicates (***p < 0.001).