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. 2022 Feb 7;12:2330. doi: 10.1038/s41598-022-06282-9

Table 1.

Association between MAGE-A6 expressions (staining intensity and H-score) and clinic-pathological parameters of BC cases (p value, Pearson’s chi-square test).

Patients and tumor characteristics Total samples N (%) Nuclear expression of MAGE-A11 Cytoplasmic expression of MAGE-A11
Staining Intensity H-score Staining Intensity H-score
Median age
Years
 ≤ 67 108 (51) 0.079 0.638
 > 67 105 (49) 0.075 0.932
Gender
Male 170 (80) 0.708 0.603
Female 43 (20) 0.839 0.372
Mean tumor size (cm)
 ≤ 2.5 134 (63) 0.741 0.139
 > 2.5 79 (37) 0.789 0.125
Histological grade
Low 94 (44) 0.349  < 0.0001
High 119 (56) 0.554  < 0.0001
pT stage
pTa 87 (40.8)
pT1 95 (44.6) 0.219  < 0.0001
pT2 31 (14.6) 0.579  < 0.0001
pT3 0 (0)
pT4 0 (0)
Lamina propria involvement
Involved 126 (59) 0.292  < 0.0001
None 87 (41) 0.954  < 0.0001
Muscularis invasion
Involved 31 (14.6) 0.14 0.334
None 182 (85.4) 0.339 0.684
Lamina propria/muscularis involvement (L/M)
L − /M- 87 (40.8) 0.219
L + /M- 95 (44.6) 0.579 0.0001
L + /M +  31 (41.6)  < 0.0001
Recurrence
Present 57 (27) 0.577 0.203
Absent 156 (73) 0.692 0.695
Distant metastasis
Present 33 (15.5) 0.262 0.097
Absent 180 (84.5) 0.49 0.932

Bold numbers represent significant p values.