Table 1.
Patients and tumor characteristics | Total samples N (%) | Nuclear expression of MAGE-A11 | Cytoplasmic expression of MAGE-A11 | ||
---|---|---|---|---|---|
Staining Intensity | H-score | Staining Intensity | H-score | ||
Median age | |||||
Years | |||||
≤ 67 | 108 (51) | 0.079 | 0.638 | ||
> 67 | 105 (49) | 0.075 | 0.932 | ||
Gender | |||||
Male | 170 (80) | 0.708 | 0.603 | ||
Female | 43 (20) | 0.839 | 0.372 | ||
Mean tumor size (cm) | |||||
≤ 2.5 | 134 (63) | 0.741 | 0.139 | ||
> 2.5 | 79 (37) | 0.789 | 0.125 | ||
Histological grade | |||||
Low | 94 (44) | 0.349 | < 0.0001 | ||
High | 119 (56) | 0.554 | < 0.0001 | ||
pT stage | |||||
pTa | 87 (40.8) | ||||
pT1 | 95 (44.6) | 0.219 | < 0.0001 | ||
pT2 | 31 (14.6) | 0.579 | < 0.0001 | ||
pT3 | 0 (0) | ||||
pT4 | 0 (0) | ||||
Lamina propria involvement | |||||
Involved | 126 (59) | 0.292 | < 0.0001 | ||
None | 87 (41) | 0.954 | < 0.0001 | ||
Muscularis invasion | |||||
Involved | 31 (14.6) | 0.14 | 0.334 | ||
None | 182 (85.4) | 0.339 | 0.684 | ||
Lamina propria/muscularis involvement (L/M) | |||||
L − /M- | 87 (40.8) | 0.219 | |||
L + /M- | 95 (44.6) | 0.579 | 0.0001 | ||
L + /M + | 31 (41.6) | < 0.0001 | |||
Recurrence | |||||
Present | 57 (27) | 0.577 | 0.203 | ||
Absent | 156 (73) | 0.692 | 0.695 | ||
Distant metastasis | |||||
Present | 33 (15.5) | 0.262 | 0.097 | ||
Absent | 180 (84.5) | 0.49 | 0.932 |
Bold numbers represent significant p values.