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. 2022 Feb 7;13:711. doi: 10.1038/s41467-022-28347-z

Fig. 5. Chk2 DNA damage checkpoint maintains GSC diapause arrest.

Fig. 5

a Schematic of a germarium showing regions 1–3 and spectrosome/fusome morphology (GSC germline stem cell, CB cystoblast, CC cyst cell). Dotted line shows region 2/3 border. bd Quantification of germline area in regions 1 and 2 (b), fusome number (c), and GSC number (d) in germaria from control and lokKD/lokP30. The control for bd is Canton S. eg Quantification of germline area in regions 1 and 2 (e), fusome number (f), and GSC number (g) in the germarium from lokKD/lokP30 treated with either ethanol vehicle (EtOH) or methoprene. Throughout Fig. 5, n = number of germaria analyzed. Data are mean ± s.e.m. from at least three independent experiments. Statistical analysis was carried out by unpaired two-tailed t test (*p = 0.0101; ***p = 0.0003; ****p < 0.0001). See also Supplementary Fig. 5.