The distinct challenges posed by digital health interventions (DHIs) for economic evaluation are not well understood.

Compared with standard technologies such as drugs and medical devices, digital technologies tend to evolve faster over time, require active user input, interact more dynamically with user and environment, have distinct pricing and lead to diffused non-health impacts.

This can have important implications for the economic evaluations of DHIs with respect to the choice of comparator, study perspective, measurement of costs and effects and type of economic analysis.