TABLE 1.
Stressor and timing | Species/strain/ sex |
Brain region | ECM component effect* | References |
Maternal separation P2-14 (3 h daily) | Rat/Wistar/male | HIP | Reelin decrease during development, increase in adulthood | Zhang et al., 2013 |
Maternal separation P1- 14 (3 h daily) | Rat/SD/male | HIP | Reelin increase in adulthood | Wang et al., 2018 |
Corticosterone injection in adulthood | Rat/SD/male | HIP, PFC | Reelin decrease in adulthood | Lebedeva et al., 2020 |
Chronic unpredictable mild stress for 6 weeks in adulthood | Mice/apoE/male | HIP, PFC | Reelin decrease in adulthood | Zhang et al., 2021 |
Chronic unpredictable stress for 6 weeks in adulthood | Rat/SD/male | HIP, FC | Laminin decrease | Laifenfeld et al., 2005a |
Social defeat during adolescence | Mice/C57/male | HIP, NAc | Laminin decrease | Rodríguez-Arias et al., 2017 |
*Compared to unstressed controls.
SD, Sprague Dawley; apoE, apolipoprotein E; FC, frontal cortex; HIP, hippocampus; PFC, prefrontal cortex; NAc, nucleus accumbens.