Overexpression of IRF4 inhibits circCdyl induced M1 polarization
(A and C) Flow cytometry plots and quantitative analysis of macrophage differentiation in Raw264.7 cells treated with or without IL-4 (20 ng/mL) and transfected with oe-vector, oe-circCdyl, or oe-circCdyl together with oe-IRF4. ∗∗p < 0.01; n = 5 per group. (B and D) Flow cytometry plots and quantitative analysis of macrophage differentiation in Raw264.7 cells treated with or without LPS (100 ng/mL) and IFN-γ (50 ng/mL) and transfected with oe-vector, oe-circCdyl, or oe-circCdyl together with oe-IRF4. ∗∗p < 0.01; n = 5 per group.